![]() ![]() Oleochemical based esters offer a very broad technology platform and enable the design of biodegradable chemistries with viscosities ranging from approximately 10cSt up to 1000cSt at 40✬. They typically have a renewability content of between 70% and 95%. Synthetic esters derived from oleochemical raw materials are the most versatile of the three categories of esters and generally result from the reaction of a petrochemical alcohol with one or more oleochemical derived fatty acids. ![]() They can be considered to fall into one of three categories: Our products have been designed for environmentally sensitive areas, are made using sustainable and renewable raw materials, and all are ultimately biodegradable and have low toxicity towards aquatic organisms.Įsters are predominantly used as base fluids in the formulation of environmentally acceptable hydraulic lubricants due to their biodegradability and low aquatic toxicity. However, there is now an increasing awareness of the impact of large amounts of lubricants entering the environment from hydraulic machinery and there is a strong movement to minimise the impact of human activity on the global environment using renewable and sustainable technologies. Hydraulic fluids based on mineral oil have been widely used due to the inherent lubricating properties and its ability to be used at elevated temperatures. Their primary function is to convey power, however a hydraulic fluid can also be vital for efficient heat transfer, lubrication and corrosion prevention. We have developed an industry-leading range of ester base fluids which provide outstanding performance benefits to hydraulic fluid formulations. Pol圜TFE and PE were the most toxic, with H5 intermediate.Hydraulic fluids play a pivotal role in the smooth operation of a well-balanced and well-designed hydraulic system. The MIL-H-83282 fluids (H8 and LT) were the least toxic hydraulic fluids. Hydrocarbon nephropathy, indicated by increased levels of hyaline droplets in kidney tubules, was severe in H5, mild in H8, LT, and Pol圜TFE (0.5 g/kg), and minimal in PE (0.5 g/kg). Peroxisomal beta oxidation, an indicator of peroxisomal proliferation, was significantly increased above control levels in the livers of all rats except the PE (0.5 g/kg) group, where the increase was not significant. Pol圜TFE (0.5 g/kg), PE (0.5 g/kg), and H5 produced an increase in absolute and relative liver weights compared to control livers. Pol圜TFE (0.5 g/kg) increased relative spleen weights, various clinical chemistry parameters, and triggered a reversible diuresis. Pol圜REAT (0.5 g/kg) decreased BW (day 11 to the end of the study) and testicular weight. ![]() Exposure to PE (0.5 g/kg) resulted in an anemia and decreases in BW (day 10 until day 25), spleen/BW ratio, blood urea nitrogen (BUN), and creatinine (CREAT). Due to their greater toxicity, resulting in lethality in the first dosing study, only 0.5 g/kg/day of PE and Pol圜TFE were administered in the second study. Exposure to H5 fluid resulted in lymphocytopenia and persistent diuresis. H8 increased alkaline phosphatase (ALKP) while LT produced an anemia and leukocytosis. Rats were initially dosed with 1.0 g/kg/day of each fluid. Oral dosing was used in order to quickly compare these fluids to Pol圜TFE, the only fluid at the time to have been tested in a 90-day inhalation study. The subchronic (26 day) oral toxicities of two AF hydraulic fluids (MIL-H-5606, MIL-H-83282 ), a commercial phosphate ester (PE), and two candidate hydraulic fluids (low temperature version of MIL-H-83282 and chlorotrifluorethylene oligomers ) were compared in male F-344 rats.
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